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5 Reasons Why Cannabis Affects Everyone Differently

5 Reasons Why Cannabis Affects Everyone Differently

Cannabis is known for its amazing medicinal and therapeutic effects. But have you ever come across someone who claims he doesn’t feel anything after consuming the herb? Well, before you toss their claim aside, let me tell you that there is definitely a possibility of this happening.

You perhaps are familiar with the fact that cannabis affects different people differently. If so, then it’s also possible that for some it doesn’t induce any effects.

But have you ever wondered why?

If you are new to the cannabis world, most likely you don’t have any idea of it. And if so, this post is made especially for you. Here are some of the most common reasons why the effects of marijuana may be different for different people.


As per the marijuana experts, your genes and genetics play a very major role in defining the effects of cannabis on you. 420 doctors claim that certain genetic traits may make you completely resistant to marijuana. While on the other hand, there are some genetic mutations that are more prone to marijuana-induced anxiety and paranoia.

As per a study, there is at least 20 percent of adults in the US that have a unique genetic mutation. Given this, their bodies have a higher than normal concentration of endocannabinoids naturally. And this makes them resistant to the common amounts of THC.


You perhaps have heard that cannabis affects men and women differently. Well, the claim doesn’t lack a scientific basis. It is one hundred percent true.

So, what’s the difference between the effects of cannabis on men and women?

First of all, the concept of marijuana-infused munchies is much more prevalent in men as compared to women. Additionally, women may benefit more from the therapeutic properties of the herb. For instance, it takes a lot less marijuana for women to experience the pain-relieving effects of marijuana.

Women also have a higher tolerance toward THC naturally, which may sometimes be a problem, as they may need a higher dosage than men to experience the same effects. Plus, they need to take the tolerance-break more often.


This is perhaps given that you feel the effects of cannabis much more easily if you are new to it as compared to someone who’s applying for an MMJ card renewal. Obviously, that person has been using the herb for a very long time. And due to this, their body has become less tolerant toward it.

However, you must also note that sometimes, even someone who’s a complete newbie may not feel a thing while trying the herb. This may be due to the body’s natural urge to resist the sudden influx of marijuana.

Pre-Existing Health Condition

Okay, let’s say you have a pre-existing medical condition, such as depression or PTSD. In that case, again, the effects of cannabis are going to feel extremely different from someone who’s healthy. But why does this happen?

As per the experts, this is something to do with the biochemistry of your body. Doctors say a medical condition can alter your body’s biochemistry significantly. And this makes the cannabinoids react to your endocannabinoid system in a very different way. There is a chance that if you have a pre-existing medical condition, cannabis does not intoxicate you at the level that it usually does. Instead, it may make you feel more normal.

Set And Setting

The set and setting in which you consume your marijuana also have a very major impact on how you feel afterward. If you are in an uncomfortable place while consuming the herb, there is a very high possibility of you having a bad high. You may feel extremely anxious and paranoid. However, consuming cannabis at a place you like and with familiar faces keeps you in your senses.

Marijuana doctors say that marijuana usually tends to amplify your current feelings. And so, if you are consuming it in an uncomfortable place, it is bound to cause further problems. Hence, it’s always advised you consume marijuana where you feel good.

So, here they are- the top reasons that make people feel the effects of cannabis differently. And now that you are aware of them, you can use the herb a lot more safely. So, don’t wait now and apply for an MMJ card now.

In light of the COVID pandemic, we advise all our patients to see a doctor online instead of visiting the clinic. Help us flatten the curve by opting for an online 420 evaluation in Temecula.